Matthias G. Wacker is an Associate Professor in the Department of Pharmacy of the National University of Singapore (NUS). Initially, he studied Pharmacy at Goethe University in Frankfurt (Germany) where he obtained his doctoral degree in pharmaceutical technology. As a principal investigator, he has joined Jennifer Dressman and Jörg Kreuter at the Institute of Pharmaceutical Technology, Goethe University. There he accomplished his habilitation1 exploring the rational design of nanocarriers and was awarded the Venia legendi in pharmaceutical technology. Before joining NUS, he headed the Department of Pharmaceutical Technology and Nanosciences of the Fraunhofer IME in Frankfurt. Currently, he serves the European Journal of Pharmaceutics and Biopharmaceutics, Frontiers in Chemistry, and the Journal of Pharmacy and Pharmacology as an editorial board member. Further, he is a scientific advisor to the Journal of Pharmaceutical Sciences editors and was guest editor for the Beilstein Journal of Nanotechnology. He was honored with the Eudragit® Best Paper Award (2014) and the Phoenix Pharmaceutics Science Award (2017) in recognition of his research excellence. From 2020-2025, he is a member of the  General Chapters – Dosage Forms Expert Committee and the Expert Panel on New Advancements in In-Vitro Product Performance Testing of the United States Pharmacopeial Convention. In his research area, he was listed in the World’s Top 2% Scientists rankings of 2022 published by Standford University2. His work is focused on the development and characterization of nanomedicines following a quality-by-design approach. He explores biopredictive release and in silico methods that can be used to establish in vitro-in vivo correlations (IVIVC). Forecasting the in-vivo performances of complex dosage forms enables a pre-selection of optimal formulation prototypes for preclinical or clinical translation.

LI Zhuoxuan

Ph.D. / Research Fellow
National University of Singapore / Wet Science Building (S9) / Level 15
Pharmacy Research Laboratories

Harshvardhan MODH

Ph.D. / Key Safety Lead and Research fellow
National University of Singapore / Wet Science Building (S9) / Level 15
Pharmacy Research Laboratories

GAN Jun Hao Kennard

Senior Research Fellow
National University of Singapore / Wet Science Building (S9) / Level 15
Pharmacy Research Laboratories

Namrata DHAKAL

Pharmacist, Ph.D. student
National University of Singapore / Wet Science Building (S9) / Level 15
Pharmacy Research Laboratories

LEONG Kok Liang Dylan

Pharmacist, Ph.D. student
National University of Singapore / Wet Science Building (S9) / Level 15
Pharmacy Research Laboratories

Elena FECIORU

External Ph.D. student (PHAST-Eurofins)
Mail: fecioru [a] em.uni-frankfurt .de

David LI

Pharmacist, Ph.D. student
National University of Singapore / Wet Science Building (S9) / Level 15
Pharmacy Research Laboratories

Shakti NAGPAL

M.Pharma, Ph.D. student
National University of Singapore / Wet Science Building (S9) / Level 15
Pharmacy Research Laboratories

WANG Tianqi

MSc student
National University of Singapore / Wet Science Building (S9) / Level 15
Pharmacy Research Laboratories

Alumni

Research Fellows

  • Bassam AL MESLMANI
  • Mukul ASHTIKAR
  • Maria GOMES
  • Saeed SHANEHSAZZADEH
  • Perumal Samy RAMAR

Ph.D. students

  • Susanne BEYER
    Thesis title: Development of nanoparticulate drug formulations for the therapy of Multiple Sclerosis.
  • Laura JABLONKA
    Thesis title: Development of physiology-based release and pharmacokinetic models for liposomal drug delivery systems
  • Christine JANAS
    Thesis title: Development of an apparatus for in vitro testing of drug release from colloidal drug carriers.
  • Fabian JUNG
    Thesis title: Development of a physiology-based pharmacokinetic model for micro- and nanoparticulate dosage forms with special consideration of environmental aspects.
  • Lisa NOTHNAGEL
    Thesis title: Development of patient-friendly drug formulations of R-flurbiprofen for the therapy of Multiple Sclerosis.
  • GAO Ge, Fiona
    Thesis title: Study on pharmacokinetics of subcutaneously injected depot formulations with biorelevant release tests and translational modeling strategies
  • Marc-Phillip MAST
    All but dissertation
  • Chantal M. WALLENWEIN
    All but dissertation

Ph.D. students (Co-Supervisor)

  • Xie KIRSAMER
  • Monica VILLA-NOVA



1 The term habilitation is derived from the Medieval Latin “habilitare“, meaning “to make suitable, to fit” and, in the German system, is obtained after several years of independent research. It is required to obtain the “venia legendi“, the permission to lecture at a university.
2 The ranking was based on a single-year snapshot of all citations in his research field in 2021 (10.17632/btchxktzyw.4).

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