In silico modeling has become an essential part of our research. When developing the methodology to measure drug release we became aware of the limited knowledge on key aspects affecting the performance of nanomedicines. To support the development of novel in vitro methods we use physiologically-based biopharmaceutics (PBB) modeling and provide these models on our website. Also, we have some models for education readily available:

 

Models 4 Education

Simulation of pharmacokinetics after peroral administration of a single dose assuming dissolution to be rate-limiting for absorption

WRG Virtual Dissolution Lab

 

Models 4 Research

Physiologically-Based Nanocarrier Biopharmaceutics (PBNB) model

In Silico Environmental Risk Assessment (ISERA) model