Wacker Research Group

Today, many drug molecules exhibit poor aqueous solubility and bioavailability. There is a...

What we Offer?

Our services and research activities all around nanotechnology

Research & Teaching

Our research and teaching activities at the National University of Singapore

Lab @ ResearchGate

The activities of our lab is accessible on ResearchGate.


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Latest News

Latest news about our research activities

Beilstein Talk: Nanomedicine

Established by the Max Planck Society in 1951, the Beilstein Institute is a non-profit organization promoting the chemical sciences. Today it publishes the free-of-charge Beilstein Journal of Nanotechnology. During the COVID pandemic, researchers made their results accessible in times of crisis and we all found value in science without barriers. This is why I am happy to support the foundation by giving the first in a series of Beilstein Talks. On the 18th of November 2020, 7 pm Singapore time (2 pm CET) I will present:

“Nanomedicine at the crossroads: Why good chemistry is not enough”

Please join the virtual event and hear my critical reflection on nanotechnology research and why interdisciplinary approaches are needed to improve current design strategies…


#sciencewithoutbarriers #releasetesting #wackerlab #nanomedicine

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Everyone wants to have access to medicines! For many years, we know that an aging population together with the quality of life we got used to leads to higher consumption of pharmaceuticals. But there’s also a rising concern that pharmaceutical drugs pollute our planet. Environmental scientists do not hesitate to say how disappointed they are with the pharmaceutical industry. Many comments indicate a total lack of understanding of the way our healthcare system works. Once a medicine has passed the clinical trials and market approval has been granted by a national authority, a company has no freedom at all to “just change the recipe”. Along this line, nanotechnology has been described to have a strong negative impact on different ecosystems.
So how are we saving our planet? Our latest research paper written by Fabian Jung was just accepted by Environmental Research. It uses release testing, a method commonly applied by the pharmaceutical industry in development, to select drug formulations that are likely to succeed during clinical trials. We are combining this technique with computer-based simulations (ISERA model) and a lifecycle assessment to pre-select the excipients used in production. Because we are stopping the use of non-sustainable excipients very early in drug development, we still have all the freedom we need to make medicines more sustainable. Additionally, we present the application of nanomaterials to reduce environmental pollution. To do so, we combine smart technologies to identify drug formulations that are effective and safe in patients without posing a risk to the environment.

Read the full story here

#ScienceSavesThePlant #EnjoyReading #WackerResearchLab #ExplainMyResearch

Illustration of drug product development using ISERA and LCA.
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